AfyaFitness20 Co-trimoxazole (septrin)

Co-trimoxazole (septrin)

Why is this medication prescribed?

Co-trimoxazole is used to treat certain bacterial infections, such as pneumonia (a lung infection), bronchitis (infection of the tubes leading to the lungs), and infections of the urinary tract, ears, and intestines. It also is
used to treat ‘travelers’ diarrhea.

Co-trimoxazole is a combination of trimethoprim and sulfamethoxazole and
is in a class of medications called sulfonamides. It works by stopping the growth of bacteria. Antibiotics will not kill viruses that can cause colds, flu, or other viral infections.

How should this medicine be used?

Co-trimoxazole comes as a tablet and a suspension (liquid) to take by mouth. It usually is taken two times a day but may be taken up to four times a day when used to treat certain severe lung infections.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Take co-trimoxazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
You should begin to feel better during the first few days of treatment with co-trimoxazole.

If your symptoms do not improve or if they get worse, call your doctor.

Shake the liquid well before each use to mix the medication evenly.
Take co-trimoxazole until you finish the prescription, even if you feel better.

Do not stop taking co-trimoxazole without talking to your doctor. If you stop taking co-trimoxazole too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.


Before you that this drug,

  1. Tell your doctor and pharmacist if you are allergic to co-trimoxazole, any other medications, or any
    ngredients in co-trimoxazole tablets and suspension. Ask your pharmacist for a list of ingredients.
    Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the
    following: amantadine; angiotensin converting enzyme inhibitors such as benazepril (Lotensin), captopril
    (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc),
    perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); anticoagulants (‘blood
    thinners’) such as warfarin (Coumadin, Jantoven); cyclosporine (Gengraf, Neoral, Sandimmune); oral
    diabetes medications such as glipizide (Glucotrol), glyburide (Diabeta, Glynase), metformin (Fortamet,
    Glucophage), pioglitazone (Actos), repaglinide (Prandin), rosiglitazone (Avandia); digoxin (Lanoxin);
    diuretics (‘water pills’); indomethacin (Indocin); leucovorin (Fusilev); medications for seizures such as phenytoin (Dilantin, Phenytek); memantine (Namenda); methotrexate (Trexall); pyrimethamine (Daraprim). and tricyclic antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), desipramine (Norpramin),
    doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil),
    and trimipramine (Surmontil).
  2. Your doctor may need to change the doses of your medications or monitor
    you carefully for side effects.
    tell your doctor if you have or have ever had thrombocytopenia (less than normal number of platelets)
    caused by taking sulfonamides or trimethoprim; megaloblastic anemia (abnormal red blood cells) caused by folate deficiency (low blood levels of folic acid), phenylketonuria (PKU, an inherited condition in which a
    special diet must be followed to prevent damage to your brain that can cause severe intellectual disability),or liver or kidney disease.
  3. Your doctor may tell you not to take co-trimoxazole. Co-trimoxazole should not
    be used in children less than 2 months of age.
    Tell your doctor if you have or have ever had severe allergies; asthma; low levels of folic acid in the body which may be caused by malnutrition (you do not eat or cannot digest the nutrients needed for good health); human immunodeficiency virus (HIV) infection; porphyria (an inherited blood disease that may cause skin or nervous system problems); thyroid disease; or glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (an inherited blood disease).
  4. Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become
    pregnant while taking co-trimoxazole, call your doctor immediately. Co-trimoxazole can harm the fetus plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Co-trimoxazole may make your skin sensitive to sunlight.

What side effects can this medication cause?

Co-trimoxazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Loss of appetite

If you experience any of the following symptoms, call your doctor immediately:

sore throat
fever or chills
severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
shortness of breath
unusual bruising or bleeding
yellowing of the skin or eyes
red or purple skin discolorations
joint or muscle pain

Leave a Reply